CRISPR-Cas9 technology represents a revolutionary advance in genetic engineering with profound implications for medicine, agriculture, and biotechnology. This comprehensive review examines current applications of CRISPR-Cas9, analyzes ethical frameworks governing gene editing research, and explores future therapeutic possibilities. We conducted systematic literature analysis of 156 peer-reviewed papers and surveyed 89 bioethicists across 15 countries regarding regulatory approaches. Our findings highlight significant regional variations in ethical perspectives, with developing nations showing greater acceptance of therapeutic gene editing. The study proposes an international framework for responsible gene editing research and education at the secondary level.